DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of ...

Cedars-Sinai researchers have created TY1, an experimental RNA-based drug that helps the body repair damaged DNA and restore injured tissue. The idea came from studying tiny molecular “messages” ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...